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This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoctoral researcher will work in an interdisciplinary team with expertise in molecular biology, biochemistry and structural biology. The project aims to understand the molecular mechanisms that govern mitochondrial DNA replication and gene expression, and how defects in these processes contribute to human disease.

Subject area 

Structural studies of mitochondrial DNA replication

Subject area description 

Mitochondrial DNA replication is essential for maintaining mtDNA integrity and stability and thereby for normal mitochondrial function and cellular energy production. Defects in the replication process can lead to mtDNA depletion or deletions and cause mitochondrial disease.

Our research aims to understand the molecular mechanisms that govern replication of human mtDNA. We combine structural biology, in vitro biochemistry and cell biology to investigate how the mitochondrial DNA replication machinery is organized and regulated. A particular focus is on structural and functional studies of the protein complexes involved in mtDNA replication and on understanding how disease-associated mutations affect these processes.

Job assignments

In this project, In this project, the postdoctoral researcher will carry out structural and functional studies of protein and protein-DNA complexes involved in mitochondrial DNA replication. A central aim will be to determine structures of replication complexes using single-particle cryo-electron microscopy (cryo-EM) and use these structures to understand how the proteins interact and regulate mtDNA replication at the molecular level.

The work will include preparation and biochemical characterization of protein complexes, cryo-EM sample preparation and grid optimization, as well as processing and structural analysis of cryo-EM data. Structural findings will be combined with in vitro biochemical analyses to test mechanistic models and investigate how disease-associated mutations affect the function of the replication machinery.

The postdoctoral researcher is expected to drive the project independently while working closely with other members of the research group and our collaborators.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 

We are seeking a highly motivated researcher with a doctoral degree in structural biology, biochemistry, molecular biology or a related field.

Documented experience in structural studies of proteins or macromolecular complexes using cryo-electron microscopy is required. Experience in protein purification and protein biochemistry is also required.

Experience in single-particle cryo-EM, including sample preparation, grid optimization, data processing and structural analysis, is particularly meritorious. Experience in structural studies of protein-DNA complexes is a strong advantage. Knowledge of mitochondrial systems and experience in cloning, mutagenesis, protein expression, cell culture and in vitro biochemical analyses are considered merits.

Great emphasis will be placed on scientific skills and the ability to independently plan, carry out and analyse research. The work involves close collaboration both within and outside the research group, making good teamwork and communication skills important. The candidate is expected to have strong scientific curiosity and the ability to work both independently and as part of an interdisciplinary team.

Excellent spoken and written English is required, as the research group operates in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

Please contact: Maria Falkenberg, Professor, e-mail: maria.falkenberg@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2026-10-02.

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/ 

Rarity Bioscience develops ultrasensitive molecular diagnostics based on our proprietary superRCA® technology, enabling detection of rare mutations that standard methods miss. As our portfolio of pharma and clinical collaborations grows, so does our Scientific Services team - and we are now looking for a Senior Scientist to help lead that work.

You will lead and contribute to scientific collaboration projects in molecular diagnostics and cancer genomics, from initial dialogue to final report. In this role, you combine scientific leadership with involvement across assay development, performance evaluation, sample testing, data interpretation, and customer dialogue. You bring enough scientific depth to be a trusted discussion partner in cancer genetics, while also being practical enough to plan experiments, assess results, provide guidance to junior colleagues, and help move projects from first dialogue to final report or publication. In addition, the role can be expected to include some hands-on lab work to build familiarity with our assays, workflows, and daily operations, with the level of involvement varying depending on project needs.

• Coordinate and execute service projects involving internal laboratory teams, academic researchers, clinical collaborators, and pharmaceutical partners.

• Plan, perform, analyze, and report laboratory work across oncology, precision medicine, and mutation detection projects.

• Analyze, interpret, and report experimental and genomic data in relation to clinical data, somatic mutation profiles, and biomarker analyses.

• Present results to customers and collaborators, and represent Rarity at scientific conferences and meetings.

• Act as a scientific and technical subject matter expert in assay development, cancer genomics, and molecular diagnostics.

• Supervise and mentor junior team members in daily operations and project work.

• Contribute to scientific publications, technical reports, and conference abstracts.

• Maintain technical documentation in line with Rarity's QMS and applicable regulatory requirements.

You will be part of a small, cross-functional team where the distance between a question and a decision is short. The role is based at our office, soon located at Uppsala Business Park, where all functions will be under one roof. Around 30 people today, growing steadily - the kind of place where you know everyone, and where what you do is visible.

You have deep knowledge of cancer genetics, built through years of working with cancer cohorts, patient data, and somatic mutation profiles. You know what variant assessment means in practice, and you can have a real scientific conversation with a pharma R&D team or a clinical researcher without losing the thread.

You can lead a project and bring people along with you. You are structured, logical, and not easily derailed but you can change course when the data tells you to. You want to work on something that matters, in a team where no one is afraid of getting their hands dirty and everyone pulls in the same direction.

• PhD in Molecular Biology, Cancer Biology, Genetics, Genomics, or a related discipline, with approximately five years of relevant experience in academia, a clinical setting, or industry. Strong MSc candidates with equivalent depth will be considered.

• Solid expertise in cancer genetics and molecular oncology, including experience working with cancer cohorts and interpreting patient and clinical data.

• Experience with variant calling, variant assessment, and interpretation of NGS data.

• Hands-on experience with molecular biology techniques such as qPCR, digital PCR, RCA, NGS-based applications, and/or flow cytometry.

• Experience in assay development, optimization, and validation.

• Strong data analysis skills — R or equivalent is an advantage.

• Excellent written and verbal communication in English.

• Experience presenting scientific results to customers, collaborators, or at conferences.

• Experience collaborating with pharmaceutical companies or translational research groups is an advantage.

Yes, it is a long list. But then again, we are not just any company - we are a team pushing the boundaries of what mutation detection can do, and we are looking for someone who is genuinely excited about that.

If this sounds like the right next step for you, submit your application no later than mid-October. We review applications on a rolling basis, so do not wait too long.

Questions about the role or the process? Reach out to Sandra Bydell Sveder, Senior Recruitment Consultant at SallyQ (sandra.sveder@sallyq.se, 0763 19 96 88).